 |
Hyaluronic acid
Bouliga
3913900090
Bouliga
20000da
25kg/bottle
COA
| molecular weight: | |
|---|---|
20000Da Low MW Acetylated HA for Cosmetic represents an innovative advancement in hyaluronic acid technology, offering enhanced skin benefits through specialized molecular modification and precise molecular weight control. This acetylated hyaluronic acid (HA) derivative combines the moisturizing properties of traditional HA with improved skin penetration and retention capabilities, making it a valuable ingredient in high-performance cosmetic formulations. With a molecular weight of 20000Da, it strikes an optimal balance between skin penetration and biological activity.
The acetylation process introduces lipophilic groups to the HA molecule, creating a dual-natured ingredient that interacts with both water and lipid components of the skin. This unique property enhances its ability to strengthen the skin barrier while providing long-lasting hydration. Cosmetic formulators value this ingredient for its versatility, as it integrates seamlessly into various product types while delivering measurable improvements in skin texture, elasticity, and moisture retention.
The acetylated modification creates an amphiphilic molecule that binds both water and skin lipids, providing dual moisturization effects. This allows it to penetrate the stratum corneum more effectively than non-acetylated HA and remain in skin tissue longer, extending hydration benefits.
At 20000Da, this low molecular weight HA balances skin penetration capability with biological activity. It is small enough to penetrate beyond the skin's surface yet large enough to exert significant moisturizing and barrier-enhancing effects in the epidermis.
Clinical testing shows that acetylated HA binds to the stratum corneum with 2x greater affinity compared to conventional HA, maintaining hydration even after multiple washes. This persistent binding ensures long-lasting moisturization for up to 12 hours after application.
The ingredient stimulates epidermal cell proliferation and supports the formation of intercellular lipids, enhancing the skin's natural barrier function. This makes it particularly effective for improving conditions associated with barrier dysfunction, such as dryness and sensitivity.
Recommended usage levels range from 0.1–1.0% depending on product type and desired effects. Serum formulations typically incorporate 0.5–1.0% for intensive treatment, while moisturizers and lotions use 0.1–0.5% for daily hydration support.
The powder form dissolves readily in water with gentle stirring, making it easy to incorporate into aqueous phases of cosmetic formulations. It should be added during the cooling phase (below 40°C) to prevent viscosity changes and maintain molecular integrity.
This acetylated HA is compatible with most cosmetic ingredients, including other humectants (glycerin, panthenol), emollients, surfactants, and active ingredients like niacinamide and vitamin C derivatives. It enhances the stability of oil-in-water emulsions by reducing droplet coalescence.
Ideal for various cosmetic products including facial serums, moisturizers, eye creams, and leave-on masks. It is particularly effective in formulations targeting dry skin, aging skin, and environmentally damaged skin requiring barrier repair.
The acetylation process significantly enhances skin retention time and barrier repair capabilities compared to non-modified low molecular weight HA. While both penetrate well, acetylated HA provides longer-lasting hydration and better integration with skin lipids.
Yes, clinical studies demonstrate excellent skin tolerance, with 0% irritation reported in patch testing across all skin types, including sensitive skin. Its barrier-strengthening properties can actually help reduce skin sensitivity over time.
Absolutely, it complements sunscreens by maintaining skin hydration during UV exposure and supporting barrier recovery post-sun exposure. It is stable in formulations containing UV filters and retains efficacy even with prolonged sun exposure.
At recommended usage levels, it increases formulation viscosity moderately, typically by 10–20% in aqueous solutions. This thickening effect is beneficial for serum and lotion formulations but should be considered in gel formulations requiring specific viscosity profiles.
Yes, in addition to moisturization, it supports collagen synthesis in the dermis and reduces transepidermal water loss, leading to measurable improvements in skin elasticity (+18% after 4 weeks) and wrinkle depth reduction (+12% after 8 weeks) in clinical studies.
20000Da Low MW Acetylated HA for Cosmetic represents an innovative advancement in hyaluronic acid technology, offering enhanced skin benefits through specialized molecular modification and precise molecular weight control. This acetylated hyaluronic acid (HA) derivative combines the moisturizing properties of traditional HA with improved skin penetration and retention capabilities, making it a valuable ingredient in high-performance cosmetic formulations. With a molecular weight of 20000Da, it strikes an optimal balance between skin penetration and biological activity.
The acetylation process introduces lipophilic groups to the HA molecule, creating a dual-natured ingredient that interacts with both water and lipid components of the skin. This unique property enhances its ability to strengthen the skin barrier while providing long-lasting hydration. Cosmetic formulators value this ingredient for its versatility, as it integrates seamlessly into various product types while delivering measurable improvements in skin texture, elasticity, and moisture retention.
The acetylated modification creates an amphiphilic molecule that binds both water and skin lipids, providing dual moisturization effects. This allows it to penetrate the stratum corneum more effectively than non-acetylated HA and remain in skin tissue longer, extending hydration benefits.
At 20000Da, this low molecular weight HA balances skin penetration capability with biological activity. It is small enough to penetrate beyond the skin's surface yet large enough to exert significant moisturizing and barrier-enhancing effects in the epidermis.
Clinical testing shows that acetylated HA binds to the stratum corneum with 2x greater affinity compared to conventional HA, maintaining hydration even after multiple washes. This persistent binding ensures long-lasting moisturization for up to 12 hours after application.
The ingredient stimulates epidermal cell proliferation and supports the formation of intercellular lipids, enhancing the skin's natural barrier function. This makes it particularly effective for improving conditions associated with barrier dysfunction, such as dryness and sensitivity.
Recommended usage levels range from 0.1–1.0% depending on product type and desired effects. Serum formulations typically incorporate 0.5–1.0% for intensive treatment, while moisturizers and lotions use 0.1–0.5% for daily hydration support.
The powder form dissolves readily in water with gentle stirring, making it easy to incorporate into aqueous phases of cosmetic formulations. It should be added during the cooling phase (below 40°C) to prevent viscosity changes and maintain molecular integrity.
This acetylated HA is compatible with most cosmetic ingredients, including other humectants (glycerin, panthenol), emollients, surfactants, and active ingredients like niacinamide and vitamin C derivatives. It enhances the stability of oil-in-water emulsions by reducing droplet coalescence.
Ideal for various cosmetic products including facial serums, moisturizers, eye creams, and leave-on masks. It is particularly effective in formulations targeting dry skin, aging skin, and environmentally damaged skin requiring barrier repair.
The acetylation process significantly enhances skin retention time and barrier repair capabilities compared to non-modified low molecular weight HA. While both penetrate well, acetylated HA provides longer-lasting hydration and better integration with skin lipids.
Yes, clinical studies demonstrate excellent skin tolerance, with 0% irritation reported in patch testing across all skin types, including sensitive skin. Its barrier-strengthening properties can actually help reduce skin sensitivity over time.
Absolutely, it complements sunscreens by maintaining skin hydration during UV exposure and supporting barrier recovery post-sun exposure. It is stable in formulations containing UV filters and retains efficacy even with prolonged sun exposure.
At recommended usage levels, it increases formulation viscosity moderately, typically by 10–20% in aqueous solutions. This thickening effect is beneficial for serum and lotion formulations but should be considered in gel formulations requiring specific viscosity profiles.
Yes, in addition to moisturization, it supports collagen synthesis in the dermis and reduces transepidermal water loss, leading to measurable improvements in skin elasticity (+18% after 4 weeks) and wrinkle depth reduction (+12% after 8 weeks) in clinical studies.
