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5kDa-50kDa Ultra-Low MW HA Powder for Serums represents a pinnacle in cosmetic ingredient technology, offering formulators a versatile hyaluronic acid powder with exceptional skin penetration capabilities. This ultra-low molecular weight (ULMW) HA is specifically engineered for high-performance serum formulations, providing superior hydration, bioavailability, and anti-aging benefits compared to standard HA ingredients. Unlike high molecular weight HA that remains on the skin's surface, this multi-range MW powder delivers active HA directly to the epidermis and upper dermis layers.
Produced through a proprietary enzymatic hydrolysis process, the powder maintains exceptional purity while achieving its ultra-low molecular weight profile. Its unique molecular weight distribution (5kDa to 50kDa) allows it to address multiple skin layers simultaneously—providing immediate surface hydration while delivering deeper anti-aging benefits. Formulators value its solubility and stability, as it integrates seamlessly into aqueous serum formulations without compromising texture or efficacy. Clinical testing shows that serums containing this HA powder increase skin hydration by 42% within 1 hour and maintain improvements for up to 24 hours.
The unique 5kDa-50kDa distribution enables multi-layer skin penetration: smaller molecules (5–15kDa) reach the deeper epidermis, medium molecules (15–30kDa) act in the upper dermis, and larger fractions (30–50kDa) provide surface hydration and barrier support. This comprehensive approach delivers both immediate and long-term benefits.
Ultra-low molecular weight HA demonstrates 3.2x greater skin penetration compared to standard low MW HA (100kDa) in Franz diffusion cell studies. This enhanced delivery system ensures HA reaches target skin cells where it can stimulate collagen production and support extracellular matrix integrity.
Undergoing 12-stage purification, the powder achieves 99.5% purity with less than 0.1% protein impurities, minimizing the risk of skin irritation. This level of purity makes it suitable for even the most sensitive skin formulations, including those targeting rosacea and post-procedure care.
The powder exhibits exceptional solubility (up to 10% in water) and stability across pH 4.0–7.5, compatible with common serum ingredients including peptides, vitamins, and antioxidants. It maintains efficacy during standard heat processing up to 60°C, providing flexibility in manufacturing.
For cosmetic serums, optimal results are achieved at 0.5–2.0% concentration. Hydrating serums typically use 0.5–1.0%, while anti-aging formulations benefit from 1.0–2.0% to maximize collagen-stimulating effects. Higher concentrations (up to 3.0%) can be used in intensive treatment serums for mature skin.
Add to the aqueous phase of formulations during cooling (below 40°C) after preservative addition. For best results, disperse powder in room temperature water with gentle stirring until fully dissolved (typically 15–20 minutes). Avoid high-shear mixing which can degrade molecular structures.
Enhances efficacy when paired with niacinamide (2–5%) for barrier repair, vitamin C derivatives (0.5–2%) for antioxidant protection, and peptides (1–5%) for collagen stimulation. This HA powder acts as a delivery vehicle, enhancing the penetration of co-formulants by up to 27% in vitro studies.
Maintains >90% activity for 24 months when stored in airtight containers at 2–25°C. In finished formulations, stability is optimized by adding 0.02–0.1% EDTA to chelate metal ions and maintaining pH between 5.0–6.5. Protect finished products from direct light exposure.
Its small molecular size allows penetration beyond the stratum corneum, delivering active HA to living skin layers where it can stimulate biological processes. Standard HA primarily provides surface hydration without these deeper anti-aging benefits.
Yes, its high purity and non-irritating profile make it suitable for all skin types, including sensitive, acne-prone, and mature skin. In patch testing with 500 subjects, it showed 0% irritation across all skin types.
Beyond hydration, it supports endogenous HA synthesis in fibroblasts, increases collagen production by 31% (in vitro), and reduces transepidermal water loss by 28% after 4 weeks of use, providing comprehensive skincare benefits.
Yes, it meets Ecocert and Cosmos standards for natural cosmetics, derived from microbial fermentation without animal sources or GMOs. It requires no synthetic solvents in production, aligning with clean beauty principles.
The powder form offers greater concentration flexibility and longer shelf life (24 months vs. 12 months for liquids). It also allows formulators to control molecular weight distribution precisely, ensuring consistent serum performance.
5kDa-50kDa Ultra-Low MW HA Powder for Serums represents a pinnacle in cosmetic ingredient technology, offering formulators a versatile hyaluronic acid powder with exceptional skin penetration capabilities. This ultra-low molecular weight (ULMW) HA is specifically engineered for high-performance serum formulations, providing superior hydration, bioavailability, and anti-aging benefits compared to standard HA ingredients. Unlike high molecular weight HA that remains on the skin's surface, this multi-range MW powder delivers active HA directly to the epidermis and upper dermis layers.
Produced through a proprietary enzymatic hydrolysis process, the powder maintains exceptional purity while achieving its ultra-low molecular weight profile. Its unique molecular weight distribution (5kDa to 50kDa) allows it to address multiple skin layers simultaneously—providing immediate surface hydration while delivering deeper anti-aging benefits. Formulators value its solubility and stability, as it integrates seamlessly into aqueous serum formulations without compromising texture or efficacy. Clinical testing shows that serums containing this HA powder increase skin hydration by 42% within 1 hour and maintain improvements for up to 24 hours.
The unique 5kDa-50kDa distribution enables multi-layer skin penetration: smaller molecules (5–15kDa) reach the deeper epidermis, medium molecules (15–30kDa) act in the upper dermis, and larger fractions (30–50kDa) provide surface hydration and barrier support. This comprehensive approach delivers both immediate and long-term benefits.
Ultra-low molecular weight HA demonstrates 3.2x greater skin penetration compared to standard low MW HA (100kDa) in Franz diffusion cell studies. This enhanced delivery system ensures HA reaches target skin cells where it can stimulate collagen production and support extracellular matrix integrity.
Undergoing 12-stage purification, the powder achieves 99.5% purity with less than 0.1% protein impurities, minimizing the risk of skin irritation. This level of purity makes it suitable for even the most sensitive skin formulations, including those targeting rosacea and post-procedure care.
The powder exhibits exceptional solubility (up to 10% in water) and stability across pH 4.0–7.5, compatible with common serum ingredients including peptides, vitamins, and antioxidants. It maintains efficacy during standard heat processing up to 60°C, providing flexibility in manufacturing.
For cosmetic serums, optimal results are achieved at 0.5–2.0% concentration. Hydrating serums typically use 0.5–1.0%, while anti-aging formulations benefit from 1.0–2.0% to maximize collagen-stimulating effects. Higher concentrations (up to 3.0%) can be used in intensive treatment serums for mature skin.
Add to the aqueous phase of formulations during cooling (below 40°C) after preservative addition. For best results, disperse powder in room temperature water with gentle stirring until fully dissolved (typically 15–20 minutes). Avoid high-shear mixing which can degrade molecular structures.
Enhances efficacy when paired with niacinamide (2–5%) for barrier repair, vitamin C derivatives (0.5–2%) for antioxidant protection, and peptides (1–5%) for collagen stimulation. This HA powder acts as a delivery vehicle, enhancing the penetration of co-formulants by up to 27% in vitro studies.
Maintains >90% activity for 24 months when stored in airtight containers at 2–25°C. In finished formulations, stability is optimized by adding 0.02–0.1% EDTA to chelate metal ions and maintaining pH between 5.0–6.5. Protect finished products from direct light exposure.
Its small molecular size allows penetration beyond the stratum corneum, delivering active HA to living skin layers where it can stimulate biological processes. Standard HA primarily provides surface hydration without these deeper anti-aging benefits.
Yes, its high purity and non-irritating profile make it suitable for all skin types, including sensitive, acne-prone, and mature skin. In patch testing with 500 subjects, it showed 0% irritation across all skin types.
Beyond hydration, it supports endogenous HA synthesis in fibroblasts, increases collagen production by 31% (in vitro), and reduces transepidermal water loss by 28% after 4 weeks of use, providing comprehensive skincare benefits.
Yes, it meets Ecocert and Cosmos standards for natural cosmetics, derived from microbial fermentation without animal sources or GMOs. It requires no synthetic solvents in production, aligning with clean beauty principles.
The powder form offers greater concentration flexibility and longer shelf life (24 months vs. 12 months for liquids). It also allows formulators to control molecular weight distribution precisely, ensuring consistent serum performance.
