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Pharmaceutical grade sodium hyaluronate is a purified form of hyaluronic acid produced through a controlled fermentation and refinement process. This material exhibits biocompatibility with human tissues and is used across multiple medical fields. The manufacturing process follows strict protocols to remove impurities, endotoxins, and microbial contaminants, ensuring compliance with international pharmaceutical standards.
This specific grade of sodium hyaluronate is formulated for ophthalmic and orthopedic applications, with molecular weight and purity levels tailored to meet the requirements of these medical specialties. It is also suitable for use in cosmetic injectables, wound care products, and drug delivery systems.
Items | Specifications | Test Results |
Appearance | White or almost white powder or fibrous aggregate | White Powder |
Infrared absorption | Matches Ph.Eur. reference spectrum of Sodium Hyaluronate | Comply |
Reaction of sodium | Positive | Positive |
Appearance of solution | Clear, absorbance NMT 0.01 at 600 nm | Clear, A₆₀₀ nm = 0.002 |
pH | 5.0-8.5 (0.5% solution) | 7.2 |
Intrinsic viscosity | Report test value | 4.2 m³/kg |
Molecular weight | Report test value | 3.2 × 10⁶ Da |
Nucleic acids | Absorbance NMT 0.5 at 260 nm | 0.007 |
Protein | ≤0.1% (on dried substance) | <LOD (0.03%) |
Chlorides | ≤0.5% | <0.5% |
Heavy metals | ≤10 ppm | <10 ppm |
Iron | ≤80 ppm (on dried substance) | <80 ppm |
Loss on drying | ≤20.0% | 8.6% |
Assay | 95.0%-105.0% (on dried substance) | 100.9% |
Residual ethanol | ≤0.5% | 0.12% |
Microbial count | ≤100 cfu/g | <10 cfu/g |
Bacterial endotoxins | <0.5 IU/mg | <0.5 IU/mg |
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In ophthalmic surgery, sodium hyaluronate functions as a viscoelastic agent. It maintains intraocular pressure and protects delicate eye tissues during procedures such as cataract extraction and intraocular lens implantation. The material's viscoelastic properties allow for precise manipulation of ocular structures while minimizing trauma.
For orthopedic use, sodium hyaluronate is injected into joints affected by osteoarthritis. It acts as a lubricant and shock absorber, reducing friction between articular surfaces and alleviating joint pain and stiffness. This treatment can improve joint mobility for patients with degenerative joint conditions.
This grade of sodium hyaluronate is also used in the production of dermal fillers for cosmetic procedures, where it restores facial volume and reduces the appearance of wrinkles. It is incorporated into wound dressings to promote moist healing environments and is being studied for use in tissue engineering and regenerative medicine applications.
Our pharmaceutical grade sodium hyaluronate is available in two standard packaging options:
1 kg units: Double plastic container inside, aluminum foil bag outside
25 kg units: Double plastic container inside, fiber drum outside
Custom packaging solutions can be arranged based on customer requirements. Orders are shipped via international express carriers including FedEx, DHL, UPS, TNT, and EMS. Delivery typically occurs within one week following payment confirmation.
Shandong Bouliga Biotechnology Co., LTD. is located in Qufu, China. The company operates a production facility equipped with manufacturing equipment for biological medicinal raw materials and an on-site laboratory. We produce a range of biomaterials including chondroitin sulfate, glucosamine hydrochloride, and collagen, in addition to sodium hyaluronate.
Our products are distributed to more than 30 domestic provinces and exported to countries including the United States, Canada, Australia, and India. We collaborate with academic institutions to advance our research and development capabilities.
This product complies with the European Pharmacopoeia (Ph.Eur.) standards for sodium hyaluronate, as verified by our infrared absorption testing and other quality control measures.
Yes, we offer pharmaceutical grade sodium hyaluronate in a range of molecular weights to suit different ophthalmic, orthopedic, and cosmetic applications.
The minimum order quantity for this product is 1 kg, packaged in the standard aluminum foil bag.
Yes, a detailed certificate of analysis is provided with every shipment, containing all test results for that specific batch of sodium hyaluronate.
